To perform cryptocurrency arbitrage, you need to find an opportunity where you can buy a cryptocurrency for less than you can sell it on another exchange (minus the fees and commission). Once you’ve found one, all you need to do is simultaneously buy Bitcoin on the lower-priced exchange and sell on the higher-priced one. It’s easy to make hundreds or even thousands of dollars in just a few seconds if you have enough funds.
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Daniel Defoe, the author of Robinson Crusoe, wrote a pamphlet in 1719, “The Anatomy of Exchange Alley or, a system of stock jobbing. Proving that scandalous trade, as it is now carry'd on, to be knavish in its private practice, and treason in its publick.” Does the sentiment sound familiar? I have republished some books from the turn of the 19th century with a preface saying basically, “Do you notice the stock market is basically unchanged even after more than a 100 years of historical turmoil?” The scams and attitudes of the market and its participants are still so recognizable after over 100 years you are left to wonder if the billions spent on compliance on the worlds bourses are not a complete waste of money.
Don’t zoom in too much on the price trends of the moment; don’t sweat the small things. It’s easy to zoom in and get stressed when Litecoin goes from $220 to $213 (or something like that). However, these little movements only matter if you are day trading large amounts of coin relative to your total investable funds. Zoom out a bit and look at trends over larger periods of time. Don’t think of that $213 relative only to $220, think of it relative to the $100 Litecoin was at a few months back, the $400 it was at after that, and the $100 it was at just a little while ago. From that perspective, a fluctuation between $220 and $213 is nearly insignificant. I will rarely make trades on timeframes shorter than 2hr candles, and I generally am looking at 6 hr and 1 day candles, because I value my sanity and am focused on the long term trajectory of crypto. That only changes in very specific instances and with purpose. If you zoom in too much, you lose sight of overarching trends (many of which are actually stronger indicators of what is actually happening).
Bitcoin has had phenomenal growth in its price and MCap since inception. If we exclude other cryptoassets, Bitcoin has been the best performing asset in the world every year since 2009 through to December 2017 with the exception of 2014. It has beaten all global currencies, equities, commodities, bonds, ETFs, real estate throughout that period. Bubbles are by definition short-lived, they do not keep bubbling for eight years.
Update 1st October 2018: The cryptocurrency market has been volatile as ever over the last 6 months. Unless you are a skilled trader, it is harder to make money in a bear market than in a bull market – and we have been in a bear market for some time now. Personally, I have stopped trading and I am now focussing on growing my portfolio passively using a cryptocurrency trading bot – you can find out more about this here.  If you are new to crypto, read on!
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Watch out for odd Altcoins and ICOs. The market is tricky enough with the major coins, it is even trickier with odd alt coins and ICOs. Yes, sometimes you can buy these low and see insane gains. In fact, getting it right is the best bet in crypto. The problem is, almost all the odd coins down the list and ICOs will spend the majority of their life being near worthless. Then, you may see a short time span in which these coins preform well. You would think that you would be able to take profits then, but so many people do not. After that one event these can end up in the graveyard. Yeah, you could make it big on low cost alts and ICOs… but I’ve seen more than a few people lose money. Be careful bottom fishing, Bitcoin might not make you rich, but it is a way less risky bet than coins further down the list.

If you are doing any active trading, set stop losses. For any coins not in your medium or long-term holds, always set stop losses. This is important for several reasons — the most obvious is mitigating your losses. But more importantly, you force yourself to decide on a point of acceptable loss, and because you now have a reference point, you are able to measure your effectiveness to keep or adjust for future trades. Sometimes, during a market dip, altcoins can plummet, and stop losses can lead to profitability by automatically selling for fiat that you can use to re-enter at lower prices.